Open Your Eyes to a More Refreshed, Lifted Look
UPNEEQ is the first and only FDA approved prescription eye drop clinically proven to lift low lying eyelids without surgery. Now available at VIOSA Aesthetics MD.
What Is UPNEEQ
UPNEEQ, or oxymetazoline hydrochloride ophthalmic solution 0.1 percent, is the first and only FDA approved prescription eye drop designed to treat acquired blepharoptosis, the clinical term for low lying or drooping upper eyelids. Just one drop per day is clinically proven to lift the upper eyelid and give your eyes a more open, awake, and refreshed appearance in minutes.
Unlike surgical eyelid correction, UPNEEQ requires no downtime, no incisions, and no recovery. It works by stimulating the Muller's muscle in the upper eyelid, the muscle responsible for eyelid elevation, causing it to contract and gently lift the lid. The result is a subtle but noticeable improvement that keeps your eyes looking alert throughout the day.
We prescribe and oversee UPNEEQ here, with Jose Ruiz, M.D., board certified in Internal Medicine. Virtual consultations are available for both new and existing patients.
Virtual Consultation
Meet with Jose Ruiz, M.D. from home. We review your health history, current medications, and symptoms to determine whether UPNEEQ is appropriate for you before anything is prescribed.
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Prefer to come see us? We are happy to evaluate you in our Northridge office and go through your options for the eye area in person, including how UPNEEQ pairs with other treatments.
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Four Reasons Patients Try UPNEEQ
UPNEEQ is the first and only prescription eye drop approved by the FDA specifically for acquired low lying eyelids in adults. Its safety and effectiveness were established across multiple clinical trials involving hundreds of patients.
If drooping eyelids have been affecting your appearance or your confidence, this is a non surgical path forward. No incisions, no anesthesia, no recovery. One drop in the morning fits into your routine.
In clinical studies, 84 percent of patients experienced some level of improvement and 74 percent had more than 50 percent improvement in eyelid lift. The average lift was roughly 1 mm, which is enough to make a visible difference.
We review your health history and current medications before prescribing, so you get the attention of a medical provider rather than just a product handed across a counter.
The Benefits of UPNEEQ
Gently elevates the eyelid for a more open, refreshed appearance.
Some patients see results in as little as 5 minutes after the first drop.
The only prescription drop approved specifically for low lying eyelids in adults.
A simple one drop routine with results lasting at least 6 hours.
A non invasive alternative to blepharoplasty with zero downtime.
Opens the eye area for a more awake, energized look.
Prescribed and monitored by Jose Ruiz, M.D., board certified in Internal Medicine.
Receive your prescription through a convenient virtual appointment from home.
See the Difference One Drop Can Make
Tired looking eyes and uneven lids no longer require surgery. UPNEEQ is a clinically proven, physician supervised option that works in minutes.
The Science and Safety Behind UPNEEQ
UPNEEQ contains oxymetazoline hydrochloride, an alpha adrenergic agonist that acts on the Muller's muscle in the upper eyelid. When one drop is applied, the active ingredient stimulates that muscle to contract, which raises the upper eyelid and opens the eye. It is the same class of active ingredient found in decongestant nasal sprays, formulated here specifically for ophthalmic use to target eyelid elevation.
Each single use vial contains enough solution to treat one or both eyes. Results have been shown to last at least 6 hours per dose in clinical studies, and some patients experience effects for up to 8 to 10 hours.
FDA approval was supported by two 6 week clinical trials involving 304 adults with acquired blepharoptosis, plus a third study confirming safety. Across those studies, 84 percent of patients experienced improvement in eyelid lift and 74 percent had more than 50 percent improvement, with an average lift of roughly 1 mm. That is clinically meaningful for both appearance and field of vision.
The most commonly observed side effects, reported in 1 to 5 percent of study participants, included mild eye inflammation, redness, dry eye, blurred vision, eye irritation, and headache. UPNEEQ is not appropriate for patients with certain underlying conditions including cardiovascular issues, uncontrolled hypertension, or specific neurological conditions. That is exactly why we require a consultation and a physician review before dispensing.
Frequently Asked Questions
UPNEEQ is approved for adults with acquired blepharoptosis, the medical term for low lying or drooping upper eyelids. Ideal candidates are adults who notice one or both eyelids sitting lower than they used to, whether from aging, prior neurotoxin treatment, or other factors. Patients with certain cardiovascular, neurological, or eye conditions may not be candidates, which is why we always require a consultation and health review first.
We offer virtual consultations, so you can meet with Jose Ruiz, M.D. from home. During the consultation we review your health history, current medications, and symptoms to determine whether UPNEEQ is right for you. If it is appropriate, we issue a prescription and walk you through the next steps. To get started, call or text our office at 562-400-7970.
Some patients in clinical studies saw visible eyelid lift in as little as 5 minutes after the first dose. Most patients experience noticeable improvement within 2 hours. A single drop has been shown to last at least 6 hours, and some patients see benefits for up to 8 to 10 hours. You apply one drop in the morning and enjoy the result through your day.
UPNEEQ is generally well tolerated. In clinical trials, side effects occurred in 1 to 5 percent of patients and included mild eye inflammation, redness, dry eye, blurred vision, eye pain or irritation at the time of use, and headache. These were generally minor and resolved without treatment. We will go through your full health history at your consultation and address any concerns before you start.
Yes. UPNEEQ is commonly used by patients who develop low lying eyelids as a side effect of a neurotoxin treatment. It can provide temporary correction while that wears off, or serve as ongoing maintenance for patients with acquired ptosis. We will review all of your current treatments and medications to determine the safest approach for your situation.
Ready to Lift, Brighten, and Refresh Your Eyes
UPNEEQ is available now at VIOSA Aesthetics MD. Call or text our office to schedule your virtual appointment with Jose Ruiz, M.D. and find out whether it is right for you.
We are currently seeing patients by appointment only. Please call or text to confirm service availability before booking.
